Chinese drug-loaded nanoporous materials were prepared from electrospinning Poly (butylenes succinate) (PBS) solutions with an additive of Chinese drug and a mixed solvent of chloroform and iso-propylalcohol in a single processing step. Characterizations of the samples, such as morphology, wettability and permeability, were studied by means of scanning electron microscope, full automatic micro droplet wettability measurement instrument and fabric air permeability performance tester. The results showed these characterizations could be controlled by adjusting electrospinning parameters such as flow rate and drug concentration. And the electrospun nanoporous materials might offer the potential for direct fabrication of biologically based and high-surface-area porous materials.