As a kind of high-performance fiber, PTFE fiber has been widely used in many fields because of its unique characteristics. In this study, pure PTFE nanofiber film was prepared effectively through electro-blown spinning (EBS) under dual forces of high speed air flow and static electric method followed by a thermal treatment process. The effects of PTFE/PVA ratio, the amount of boric acid (BA), air pressure, applied voltage and sintered temperature were discussed to obtain the PTFE nanofibers with different diameters, and the film had been characterized by SEM, TG, XRD and XPS, respectively. The results showed that pure PTFE nanofiber film with good morphology could be large scale prepared through the EBS process. Moreover, this novel EBS method may realize the industrialized production of high performance polymer fibers. (C) 2016 Elsevier B.V. All rights reserved.