In this work, a novel nanofiber network of colloidal semiconductor CdSe/CdS nanoplatelets (NPLs)/polyvinylpyrrolidone (PVP) with characteristics of porous membranes has successfully been fabricated via the electrospinning technique, in which NPLs and PVP were used as fluorescence agent and fiber matrix, respectively. Firstly, the CdSe core NPLs with quasi 2D geometry was synthesized, and the epitaxial growth of the CdS shells was performed by the atomic layer deposition (c-ALD) method at room temperature. CdSe/CdS core-shell NPLs with a narrow, ca. 20 nm photoluminescence band were blended with PVP dissolved in ethanol-trichloroethylene mixture; and hybrid polymer-NPLs fibers were obtained through the electrospinning technique. The final nanofiber network exhibits the excellent optical properties of the NPLs, which has potential for separation and absorption of pollutants and isolation of microorganisms.